The Multifaceted Role of FUT8 in Tumorigenesis: From Pathways to Potential Clinical Applications
FUT8, the sole glycosyltransferase responsible for N-glycan core fucosylation, plays a crucial role in tumorigenesis and development. Aberrant FUT8 expression disrupts the function of critical cellular components and triggers the abnormality of tumor signaling pathways, leading to malignant transfor...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-01-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/25/2/1068 |