The Multifaceted Role of FUT8 in Tumorigenesis: From Pathways to Potential Clinical Applications

The Multifaceted Role of FUT8 in Tumorigenesis: From Pathways to Potential Clinical Applications

FUT8, the sole glycosyltransferase responsible for N-glycan core fucosylation, plays a crucial role in tumorigenesis and development. Aberrant FUT8 expression disrupts the function of critical cellular components and triggers the abnormality of tumor signaling pathways, leading to malignant transfor...

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Bibliographic Details
Main Authors:	Meng Shi, Xin-Rui Nan, Bao-Qin Liu
Format:	Article
Language:	English
Published:	MDPI AG 2024-01-01
Series:	International Journal of Molecular Sciences
Subjects:	FUT8 core fucosylation malignancy pathway tumor
Online Access:	https://www.mdpi.com/1422-0067/25/2/1068

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