Quality control of cytoplasmic proteins inside the nucleus
A complex network of molecular chaperones and proteolytic machinery safeguards the proteins which comprise the proteome, from the time they are synthesized on ribosomes to their destruction via proteolysis. Impaired protein quality control results in the accumulation of aberrant proteins, which may...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
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Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037022003671 |