Culture of Hoffa fat pad mesenchymal stem/stromal cells on microcarrier suspension in vertical wheel bioreactor for extracellular vesicle production

Culture of Hoffa fat pad mesenchymal stem/stromal cells on microcarrier suspension in vertical wheel bioreactor for extracellular vesicle production

Abstract Background Mesenchymal stromal cells (MSCs) are increasingly employed in regenerative medicine approaches for their immunomodulatory and anti-inflammatory properties, which are encoded in their secretome including extracellular vesicles (EVs). The Hoffa fat pad (HFP) located infrapatellarly...

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Bibliographic Details
Main Authors: Alexander Otahal, Karina Kramer, Markus Neubauer, Slavomira Gulová, Zsombor Lacza, Stefan Nehrer, Andrea De Luna
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cell
Extracellular vesicle
Bioreactor
3D-culture
Cartilage
Hoffa fat pad
Online Access:https://doi.org/10.1186/s13287-024-03681-9

Internet

https://doi.org/10.1186/s13287-024-03681-9

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