Differential Transcriptional Regulation of Polymorphic p53 Codon 72 in Metabolic Pathways

Differential Transcriptional Regulation of Polymorphic p53 Codon 72 in Metabolic Pathways

p53 is a transcription factor that is activated under DNA damage stress and regulates the expression of proapoptotic genes including the expression of growth arrest genes to subsequently determine the fate of cells. To investigate the functional differences of polymorphic p53 codon 72, we constructe...

Full description

Bibliographic Details
Main Authors: Bu-Yeo Kim, Seo-Young Lee, Sun-Ku Chung
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
polymorphic p53 codon 72
induced pluripotent stem cell
DNA damage stress
growth arrest
apoptosis
metabolic signaling pathway
Online Access:https://www.mdpi.com/1422-0067/22/19/10793

Internet

https://www.mdpi.com/1422-0067/22/19/10793

Similar Items