Design of the New <i>Closo</i>-Dodecarborate-Containing Gemcitabine Analogue for the Albumin-Based Theranostics Composition

Design of the New <i>Closo</i>-Dodecarborate-Containing Gemcitabine Analogue for the Albumin-Based Theranostics Composition

Combination therapy is becoming an increasingly important treatment strategy because multi-drugs can maximize therapeutic effect and overcome potential mechanisms of drug resistance. A new albumin-based theranostic containing gemcitabine <i>closo</i>-dodecaborate analogue has been develo...

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Bibliographic Details
Main Authors: Valeria I. Raskolupova, Meiling Wang, Maya A. Dymova, Gleb O. Petrov, Ivan M. Shchudlo, Sergey Yu. Taskaev, Tatyana V. Abramova, Tatyana S. Godovikova, Vladimir N. Silnikov, Tatyana V. Popova
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
boron neutron capture therapy
boron delivery agents
gemcitabine analogue
boronated albumin theranostic conjugate
cell viability and proliferation
clonogenic assay
Online Access:https://www.mdpi.com/1420-3049/28/6/2672

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https://www.mdpi.com/1420-3049/28/6/2672

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