Resistance mutations of NS3 and NS5b in treatment-naïve patients infected with hepatitis C virus in Santa Catarina and Rio Grande do Sul states, Brazil

Resistance mutations of NS3 and NS5b in treatment-naïve patients infected with hepatitis C virus in Santa Catarina and Rio Grande do Sul states, Brazil

Abstract Hepatitis C virus (HCV) infection is a worldwide health problem. Nowadays, direct-acting antiviral agents (DAAs) are the main treatment for HCV; however, the high level of virus variability leads to the development of resistance-associated variants (RAVs). Thus, assessing RAVs in infected p...

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Bibliographic Details
Main Authors: Elisabete Andrade, Daniele Rocha, Marcela Fontana-Maurell, Elaine Costa, Marisa Ribeiro, Daniela Tupy de Godoy, Antonio G.P. Ferreira, Amilcar Tanuri, Rodrigo Brindeiro, Patrícia Alvarez
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2020-02-01
Series:Genetics and Molecular Biology
Subjects:
Direct-acting antivirals
resistance-associated substitutions
blood donors
NS3
NS5b
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000100107&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000100107&tlng=en

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