Lipidomic Characterization of Oocytes at Single-Cell Level Using Nanoflow Chromatography-Trapped Ion Mobility Spectrometry-Mass Spectrometry

Lipidomic Characterization of Oocytes at Single-Cell Level Using Nanoflow Chromatography-Trapped Ion Mobility Spectrometry-Mass Spectrometry

Mass spectrometry (MS)-based lipidomic has become a powerful tool for studying lipids in biological systems. However, lipidome analysis at the single-cell level remains a challenge. Here, we report a highly sensitive lipidomic workflow based on nanoflow liquid chromatography and trapped ion mobility...

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Bibliographic Details
Main Authors: Pujia Zhu, Guowei Bu, Ruifeng Hu, Xianqin Ruan, Rongrong Fu, Zhourui Zhang, Qiongqiong Wan, Xin Liu, Yiliang Miao, Suming Chen
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
mass spectrometry
lipidomic
single-cell
oocytes
liquid chromatography
Online Access:https://www.mdpi.com/1420-3049/28/10/4202

Internet

https://www.mdpi.com/1420-3049/28/10/4202

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