The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds

The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds

The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin (mTOR) signaling pathway has been implicated in various immune-mediated inflammatory and hyperproliferative dermatoses such as acne, atopic dermatitis, alopecia, psoriasis, wounds, and vitiligo, and is associated...

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Bibliographic Details
Main Authors: Tithi Roy, Samuel T. Boateng, Mohammad B. Uddin, Sergette Banang-Mbeumi, Rajesh K. Yadav, Chelsea R. Bock, Joy T. Folahan, Xavier Siwe-Noundou, Anthony L. Walker, Judy A. King, Claudia Buerger, Shile Huang, Jean Christopher Chamcheu
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
acne
PI3K-Akt-mTOR signaling pathway
skin inflammation
phytochemicals
psoriasis
atopic dermatitis
Online Access:https://www.mdpi.com/2073-4409/12/12/1671

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https://www.mdpi.com/2073-4409/12/12/1671

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