Control of glutamate release by complexes of adenosine and cannabinoid receptors

Control of glutamate release by complexes of adenosine and cannabinoid receptors

Abstract Background It has been hypothesized that heteromers of adenosine A2A receptors (A2AR) and cannabinoid CB1 receptors (CB1R) localized in glutamatergic nerve terminals mediate the integration of adenosine and endocannabinoid signaling involved in the modulation of striatal excitatory neurotra...

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Bibliographic Details
Main Authors: Attila Köfalvi, Estefanía Moreno, Arnau Cordomí, Ning-Sheng Cai, Victor Fernández-Dueñas, Samira G. Ferreira, Ramón Guixà-González, Marta Sánchez-Soto, Hideaki Yano, Verònica Casadó-Anguera, Rodrigo A. Cunha, Ana Maria Sebastião, Francisco Ciruela, Leonardo Pardo, Vicent Casadó, Sergi Ferré
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Biology
Subjects:
Adenosine A2A receptor
Cannabinoid CB1 receptor
GPCR heteromers
Adenylyl cyclase
Glutamate transmission
Striatum
Online Access:https://doi.org/10.1186/s12915-020-0739-0

Internet

https://doi.org/10.1186/s12915-020-0739-0

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