Flavonoid Rutin Presented Anti-Glioblastoma Activity Related to the Modulation of Onco miRNA-125b Expression and STAT3 Signaling and Impact on Microglia Inflammatory Profile

Glioblastoma (GBM) is the most aggressive and treatment-resistant brain tumor. In the GBM microenvironment, interaction with microglia is associated with the dysregulation of cytokines, chemokines, and miRNAs, contributing to angiogenesis, proliferation, anti-apoptosis, and chemoresistance. The flav...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Irlã Santos Lima, Érica Novaes Soares, Carolina Kymie Vasques Nonaka, Bruno Solano de Freitas Souza, Balbino Lino dos Santos, Silvia Lima Costa
التنسيق: مقال
اللغة:English
منشور في: MDPI AG 2024-01-01
سلاسل:Brain Sciences
الموضوعات:
الوصول للمادة أونلاين:https://www.mdpi.com/2076-3425/14/1/90