Neurotrophic factors-based therapeutic strategies in the spinal cord injury: an overview of recent preclinical studies in rodent models

Abstract Following the traumatic spinal cord injury (SCI) and initial mechanical insult, a cascade of secondary cellular and molecular events occurs at the trauma site. This phenomenon develops a toxic lesion environment with an inhibitory effect on axonal regeneration. The complicated pathophysiolo...

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Bibliographic Details
Main Authors: Nazila Deznabi, Samaneh Hosseini, Mojgan Rajabi
Format: Article
Language:English
Published: SpringerOpen 2023-05-01
Series:The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Subjects:
Online Access:https://doi.org/10.1186/s41983-023-00661-3