Citrate cross-feeding by Pseudomonas aeruginosa supports lasR mutant fitness

Citrate cross-feeding by Pseudomonas aeruginosa supports lasR mutant fitness

ABSTRACTCross-feeding of metabolites between subpopulations can affect cell phenotypes and population-level behaviors. In chronic Pseudomonas aeruginosa lung infections, subpopulations with loss-of-function (LOF) mutations in the lasR gene are common. LasR, a transcription factor often described for...

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Bibliographic Details
Main Authors: Dallas L. Mould, Carson E. Finger, Amy Conaway, Nico Botelho, Stacie E. Stuut, Deborah A. Hogan
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mBio
Subjects:
quorum sensing
citrate
catabolite repression
cross-feeding
LasR
CbrA
Online Access:https://journals.asm.org/doi/10.1128/mbio.01278-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01278-23

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