Shengma Biejia Decoction Inhibits Cell Growth in Multiple Myeloma by Inducing Autophagy-Mediated Apoptosis Through the ERK/mTOR Pathway

Shengma Biejia Decoction Inhibits Cell Growth in Multiple Myeloma by Inducing Autophagy-Mediated Apoptosis Through the ERK/mTOR Pathway

Shengma Biejia decoction (SMBJD), a traditional Chinese formula recorded in the Golden Chamber, has been widely used for the treatment of malignant tumors. However, its underlying molecular targets and mechanisms are still unclear. This study showed that SMBJD inhibited tumor growth and stimulated h...

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Bibliographic Details
Main Authors: Huibo Dai, Bangyun Ma, Xingbin Dai, Jie Pang, Jingyu Wang, Yandong Zhao, Mengya Wang, Hong Zhang, Haoran Gao, Shushu Qian, Fang Tian, Xuemei Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
shengma biejia decoction
multiple myeloma
autophagy
apoptosis
ERK/mTOR pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.585286/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.585286/full

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