Overlooked Candida glabrata petites are echinocandin tolerant, induce host inflammatory responses, and display poor in vivo fitness

Overlooked Candida glabrata petites are echinocandin tolerant, induce host inflammatory responses, and display poor in vivo fitness

ABSTRACT Small colony variants are relatively common among some bacterial species and are associated with poor prognosis and recalcitrant infections. Similarly, Candida glabrata—a major intracellular fungal pathogen—produces small and slow-growing respiratory-deficient colonies, termed “petite.” Des...

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Bibliographic Details
Main Authors: Amir Arastehfar, Farnaz Daneshnia, Hrant Hovhannisyan, Diego Fuentes, Nathaly Cabrera, Christopher Quinteros, Macit Ilkit, Nevzat Ünal, Suleyha Hilmioğlu-Polat, Kauser Jabeen, Sadaf Zaka, Jigar V. Desai, Cornelia Lass-Flörl, Erika Shor, Toni Gabaldon, David S. Perlin
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
Candida glabrata
petite
toelrance
drug resistance
Online Access:https://journals.asm.org/doi/10.1128/mbio.01180-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01180-23

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