Transmission of tauopathy strains is independent of their isoform composition
Although normal human brains express 6 tau isoforms in equal ratio with 3 or 4 microtubule-binding repeat domains (3R and 4R), tau inclusions from different human tauopathy brains, now considered as different strains, have distinct isoform compositions and strain properties and the relationship betw...
Հիմնական հեղինակներ: | , , , , , , , , , , , , |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
Nature Portfolio
2020-01-01
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Շարք: | Nature Communications |
Առցանց հասանելիություն: | https://doi.org/10.1038/s41467-019-13787-x |