Transmission of tauopathy strains is independent of their isoform composition
Although normal human brains express 6 tau isoforms in equal ratio with 3 or 4 microtubule-binding repeat domains (3R and 4R), tau inclusions from different human tauopathy brains, now considered as different strains, have distinct isoform compositions and strain properties and the relationship betw...
المؤلفون الرئيسيون: | , , , , , , , , , , , , |
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التنسيق: | مقال |
اللغة: | English |
منشور في: |
Nature Portfolio
2020-01-01
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سلاسل: | Nature Communications |
الوصول للمادة أونلاين: | https://doi.org/10.1038/s41467-019-13787-x |