A comprehensive assessment of exome capture methods for RNA sequencing of formalin-fixed and paraffin-embedded samples

Abstract RNA-Seq analysis of Formalin-Fixed and Paraffin-Embedded (FFPE) samples has emerged as a highly effective approach and is increasingly being used in clinical research and drug development. However, the processing and storage of FFPE samples are known to cause extensive degradation of RNAs,...

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Bibliographic Details
Main Authors: Liang Zong, Yabing Zhu, Yuan Jiang, Ying Xia, Qun Liu, Sanjie Jiang
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-023-09886-1