Research Progress of CD47-SIRPα Signaling Axis as An Innate Immune Checkpoint in Cancer

Immune checkpoint inhibitors, including those targeting CTLA-4/B7 and PD-1/PD-L1 inhibitory pathways, are now available for clinical use on cancer patients. Other interesting checkpoint inhibitors are currently under the development. CD47 is a protein broadly expressed on the surface of normal cells...

Full description

Bibliographic Details
Main Authors: ZHA Li, YU Jiaojiao, XU Bin
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2018-08-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2018.18.0217.htm