Hierarchical partitioning of metazoan protein conservation profiles provides new functional insights.

The availability of many complete, annotated proteomes enables the systematic study of the relationships between protein conservation and functionality. We explore this question based solely on the presence or absence of protein homologues (a.k.a. conservation profiles). We study 18 metazoans, from...

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Bibliographic Details
Main Authors: Jonathan Witztum, Erez Persi, David Horn, Metsada Pasmanik-Chor, Benny Chor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090282&type=printable