Adenosine A<sub>3</sub> Receptor (A<sub>3</sub>AR) Agonist for the Treatment of Bleomycin-Induced Lung Fibrosis in Mice

Adenosine A<sub>3</sub> Receptor (A<sub>3</sub>AR) Agonist for the Treatment of Bleomycin-Induced Lung Fibrosis in Mice

Adenosine receptors (ARs) are involved in the suppression and development of inflammatory and fibrotic conditions. Specifically, AR activation promotes differentiation of lung fibroblasts into myofibroblasts, typical of a fibrotic event. Pulmonary fibrosis is a severe disease characterized by inflam...

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Bibliographic Details
Main Authors: Silvia Sgambellone, Silvia Marri, Stefano Catarinicchia, Alessandro Pini, Dilip K. Tosh, Kenneth A. Jacobson, Emanuela Masini, Daniela Salvemini, Laura Lucarini
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
adenosine A<sub>3</sub> receptor
inflammation
lung fibrosis
A<sub>3</sub>AR agonist
MRS5980
Online Access:https://www.mdpi.com/1422-0067/23/21/13300

Internet

https://www.mdpi.com/1422-0067/23/21/13300

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