High-Payload Buccal Delivery System of Amorphous Curcumin–Chitosan Nanoparticle Complex in Hydroxypropyl Methylcellulose and Starch Films

High-Payload Buccal Delivery System of Amorphous Curcumin–Chitosan Nanoparticle Complex in Hydroxypropyl Methylcellulose and Starch Films

Oral delivery of curcumin (CUR) has limited effectiveness due to CUR’s poor systemic bioavailability caused by its first-pass metabolism and low solubility. Buccal delivery of CUR nanoparticles can address the poor bioavailability issue by virtue of avoidance of first-pass metabolism and solubility...

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Bibliographic Details
Main Authors: Li Ming Lim, Kunn Hadinoto
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
curcumin
nanoparticle complex
buccal drug delivery
polysaccharides
Online Access:https://www.mdpi.com/1422-0067/22/17/9399

Internet

https://www.mdpi.com/1422-0067/22/17/9399

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