In vitro modelling of human proprioceptive sensory neurons in the neuromuscular system

Abstract Proprioceptive sensory neurons (pSN) are an essential and undervalued part of the neuromuscular circuit. A protocol to differentiate healthy and amyotrophic lateral sclerosis (ALS) human neural stem cells (hNSC) into pSN, and their comparison with the motor neuron (MN) differentiation proce...

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Bibliographic Details
Main Authors: Maider Badiola-Mateos, Tatsuya Osaki, Roger Dale Kamm, Josep Samitier
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23565-3