HER-3 surface expression increases in advanced colorectal cancer representing a potential therapeutic target

Abstract HER-3 (also known as ErbB-3) is a human epidermal growth factor receptor tyrosine kinases family member, and its expression in CRC (colorectal cancer) tissues was previously associated with poor prognosis. In this study, HER-3 expression was analyzed by immunohistochemistry in two cohorts o...

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Bibliographic Details
Main Authors: Emily Capone, Thordur Tryggvason, Ilaria Cela, Beatrice Dufrusine, Morena Pinti, Francesco Del Pizzo, Helga Sigrun Gunnarsdottir, Tommaso Grottola, Vincenzo De Laurenzi, Stefano Iacobelli, Rossano Lattanzio, Gianluca Sala
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01692-8