Modeling neural differentiation on micropatterned substrates coated with neural matrix components

Modeling neural differentiation on micropatterned substrates coated with neural matrix components

Topographical and biochemical characteristics of the substrate are critical for neuronal differentiation including axonal outgrowth and regeneration of neural circuits in vivo. Contact stimuli and signaling molecules allow neurons to develop and stabilize synaptic contacts. Here we present the devel...

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Bibliographic Details
Main Authors: Patricia eGarcía-Parra, Fabio eCavaliere, Marcos eMaroto, Leire eBilbao, Isabel eObieta, Adolfo eLópez de Munain, José Iñaki eÁlava, Ander eIzeta
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neural differentiation
ECM (extracellular matrix)
micropatterning
Nerve tissue engineering
Photolithography
progenitor cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2012.00010/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2012.00010/full

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