Ubiquitin-specific protease 14 targets PFKL-mediated glycolysis to promote the proliferation and migration of oral squamous cell carcinoma

Ubiquitin-specific protease 14 targets PFKL-mediated glycolysis to promote the proliferation and migration of oral squamous cell carcinoma

Abstract Aberrant upregulation of the ubiquitin-specific protease 14 (USP14) has been found in some malignant tumors, including oral squamous cell carcinoma (OSCC). In this study, we further demonstrated that aberrantly overexpressed USP14 was also closely related to adverse clinicopathological feat...

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Bibliographic Details
Main Authors: Xingming Zhang, Lou Geng, Yi Tang, Yingying Wang, Youping Zhang, Chujiao Zhu, Hu Lei, Hanzhang Xu, Qi Zhu, Yingli Wu, Wenli Gu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Translational Medicine
Subjects:
USP14
Deubiquitination
PFKL
Glycolysis
OSCC
Online Access:https://doi.org/10.1186/s12967-024-04943-z

Internet

https://doi.org/10.1186/s12967-024-04943-z

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