Exercise Training Attenuates Hypertension via Suppressing ROS/MAPK/NF-κB/AT-1R Pathway in the Hypothalamic Paraventricular Nucleus

Exercise Training Attenuates Hypertension via Suppressing ROS/MAPK/NF-κB/AT-1R Pathway in the Hypothalamic Paraventricular Nucleus

Background: Aerobic exercise training (ExT) is beneficial for hypertension, however, its central mechanisms in improving hypertension remain unclear. Since the importance of the up-regulation of angiotensin II type 1 receptor (AT-1R) in the paraventricular nucleus (PVN) of the hypothalamic in sympat...

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Bibliographic Details
Main Authors: Jie Qi, Rui-Juan Li, Li-Yan Fu, Kai-Li Liu, Jin-An Qiao, Yu Yang, Xiao-Jing Yu, Jia-Yue Yu, Ying Li, Hong Tan, Yu-Ming Kang
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Nutrients
Subjects:
exercise training
paraventricular nucleus
hypertension
angiotensin II type 1 receptor
MAPK
Online Access:https://www.mdpi.com/2072-6643/14/19/3968

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https://www.mdpi.com/2072-6643/14/19/3968

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