Mutated WWP1 Induces an Aberrant Expression of Myosin Heavy Chain Gene in C2C12 Skeletal Muscle Cells

The WW domain containing E3 ubiquitin protein ligase 1 (WWP1), an enzyme to degrade unneeded or damaged proteins, was recently identified as the responsible for chicken muscular dystrophy. Despite of intensive studies on oncogenic characters, the role of WWP1 to muscular diseases has not yet been f...

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Bibliographic Details
Main Authors: Hirokazu Matsumoto, Yumi Inba, Shinji Sasazaki, Akira Fujiwara, Nobutsune Ichihara, Tateki Kikuchi, Hideyuki Mannen
Format: Article
Language:English
Published: Japan Poultry Science Association 2010-04-01
Series:The Journal of Poultry Science
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jpsa/47/2/47_009107/_pdf/-char/en