5-Aza-2’-deoxycytidine inhibits retinoblastoma cell by reactivating epigenetically silenced </b><i><b>RASSF1A</b></i><b> gene

5-Aza-2’-deoxycytidine inhibits retinoblastoma cell by reactivating epigenetically silenced </b><i><b>RASSF1A</b></i><b> gene

<b>AIM:</b>To investigate the effect of 5-Aza-2’-deoxycytidine (5-Aza-CdR), a DNA methyltransferase (DNMT) inhibitor, on the growth and survival of the Chinese retinoblastoma (RB) cell line HXO-RB44.<b>METHODS:</b>The DNA methylation status of the Ras association domain famil...

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Bibliographic Details
Main Authors: Ru Liu, Xiao-Huan Zhang, Kun Zhang, Wei Li, Wen-Jun Wang, Di-Xian Luo, Ling Gao
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2014-02-01
Series:International Journal of Ophthalmology
Subjects:
5-Aza-2’-deoxycytidine
retinoblastoma
methylation
apoptosis
Ras association domain family
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949458/

Internet

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949458/

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