Thyroid transcription factor 1 (TTF‐1) negativity as a predictor of unfavorable response to EGFR‐TKI therapy in advanced lung adenocarcinoma patients with EGFR mutations

Thyroid transcription factor 1 (TTF‐1) negativity as a predictor of unfavorable response to EGFR‐TKI therapy in advanced lung adenocarcinoma patients with EGFR mutations

Abstract Background The absence of thyroid transcription factor 1 (TTF‐1) is associated with a lower frequency of epidermal growth factor receptor (EGFR) mutations in lung adenocarcinoma (LUAD). The aim of this study was to assess the impact of TTF‐1 expression on the clinical response to EGFR‐tyros...

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Bibliographic Details
Main Authors: Xiaosheng Ding, Weiwei Shi, Bingxuan Han, Hanxiao Chen, Jia Li, Juan An, Lili Zhou, Weiran Xu, Hui Shi, Xixi Zheng, Yichun Hua, Xiaoyan Li
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Thoracic Cancer
Subjects:
efficacy
EGFR tyrosine kinase inhibitor
epidermal growth factor receptor
lung adenocarcinoma
thyroid transcription factor 1
Online Access:https://doi.org/10.1111/1759-7714.15079

Internet

https://doi.org/10.1111/1759-7714.15079

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