From Flies to Mice: The Emerging Role of Non-Canonical PRC1 Members in Mammalian Development

From Flies to Mice: The Emerging Role of Non-Canonical PRC1 Members in Mammalian Development

Originally two types of Polycomb Repressive Complexes (PRCs) were described, canonical PRC1 (cPRC1) and PRC2. Recently, a versatile set of complexes were identified and brought up several dilemmas in PRC mediated repression. These new class of complexes were named as non-canonical PRC1s (ncPRC1s). B...

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Bibliographic Details
Main Authors: Izabella Bajusz, Gergő Kovács, Melinda K. Pirity
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Epigenomes
Subjects:
Polycomb repression
epigenetic regulation
dynamic gene expression
non-canonical
PRC1
RING1
RYBP
covalent histone modification
embryonic stem cells
differentiation
Online Access:http://www.mdpi.com/2075-4655/2/1/4

Internet

http://www.mdpi.com/2075-4655/2/1/4

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