A role for endothelial alpha-mannosidase MAN1C1 in radiation-induced immune cell recruitment

A role for endothelial alpha-mannosidase MAN1C1 in radiation-induced immune cell recruitment

Summary: Radiation therapy damages tumors and normal tissues, probably in part through the recruitment of immune cells. Endothelial high-mannose N-glycans are, in particular, involved in monocyte-endothelium interactions. Trimmed by the class I α-mannosidases, these structures are quite rare in norm...

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Bibliographic Details
Main Authors: Ségolène Ladaigue, Anne-Charlotte Lefranc, Khadidiatou Balde, Monica Quitoco, Emilie Bacquer, Didier Busso, Guillaume Piton, Jordane Dépagne, Nathalie Déchamps, Nao Yamakawa, Louise Debusschere, Chunxue Han, Fabrice Allain, Valérie Buard, Georges Tarlet, Agnès François, Vincent Paget, Fabien Milliat, Olivier Guipaud
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Biochemistry
Immunology
Cell biology
Functional aspects of cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222017540

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http://www.sciencedirect.com/science/article/pii/S2589004222017540

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