Sphk1 regulates HMGB1 via HDAC4 and mediates epithelial pyroptosis in allergic rhinitis

Sphk1 regulates HMGB1 via HDAC4 and mediates epithelial pyroptosis in allergic rhinitis

Background: Allergic rhinitis (AR) is a global health issue affecting millions of individuals worldwide. Pyroptosis has emerged as a major player in the development of AR, and targeting its inhibition with specific drugs holds promise for AR treatment. However, a comprehensive understanding of the p...

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Bibliographic Details
Main Authors: Wei Huang, MM, Xi Chen, MM, Zizhen Liu, MM, Changwu Li, MD, Xin Wei, MD, Jiabin Zhan, MD, Quan Qiu, MM, Jing Zheng, MD
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:World Allergy Organization Journal
Subjects:
Sphingosine kinase 1
HMGB1
HDAC4
Pyroptosis
Rhinitis
Allergic
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455124000942

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http://www.sciencedirect.com/science/article/pii/S1939455124000942

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