CXCL14 Attenuates Triple-Negative Breast Cancer Progression by Regulating Immune Profiles of the Tumor Microenvironment in a T Cell-Dependent Manner

CXCL14 Attenuates Triple-Negative Breast Cancer Progression by Regulating Immune Profiles of the Tumor Microenvironment in a T Cell-Dependent Manner

Triple-negative breast cancer (TNBC) is aggressive and has a poor overall survival due to a lack of therapeutic targets compared to other subtypes. Chemokine signature revealed that TNBC had low levels of CXCL14, an orphan homeostatic chemokine to regulate the immune network. Here, we investigated i...

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Bibliographic Details
Main Authors: Carla Gibbs, Jae Young So, Abdul Ahad, Aleksandra M. Michalowski, Deok-Soo Son, Yang Li
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
triple-negative breast cancer
tumor microenvironment
chemokines
CXCL14
immune profiles
Online Access:https://www.mdpi.com/1422-0067/23/16/9314

Internet

https://www.mdpi.com/1422-0067/23/16/9314

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