Crocin Attenuates NLRP3 Inflammasome Activation by Inhibiting Mitochondrial Reactive Oxygen Species and Ameliorates Monosodium Urate-Induced Mouse Peritonitis

Crocin Attenuates NLRP3 Inflammasome Activation by Inhibiting Mitochondrial Reactive Oxygen Species and Ameliorates Monosodium Urate-Induced Mouse Peritonitis

Crocin is a hydrophilic carotenoid pigment found in the stigma of <i>Crocus sativus</i> or the fruit of <i>Gardenia jasminoides</i>. In this study, we investigated the effects of Crocin on the activation of the nucleotide-binding oligomerization domain, leucine-rich repeat, a...

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Bibliographic Details
Main Authors: Ruth Sangare, Iskander Madhi, Ji-Hee Kim, YoungHee Kim
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Current Issues in Molecular Biology
Subjects:
Crocin
mitochondrial membrane potential
mitochondrial reactive oxygen species
NLRP3 inflammasome
pyroptosis
peritonitis
Online Access:https://www.mdpi.com/1467-3045/45/3/134

Internet

https://www.mdpi.com/1467-3045/45/3/134

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