Direct nucleophilic and electrophilic activation of alcohols using a unified boron-based organocatalyst scaffold

Abstract Organocatalytic strategies for the direct activation of hydroxy-containing compounds have paled in comparison to those applicable to carbonyl compounds. To this end, boronic acids have emerged as valuable catalysts for the functionalization of hydroxy groups in a mild and selective fashion....

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Bibliographic Details
Main Authors: Jason P. G. Rygus, Dennis G. Hall
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38228-8