18F-FET microPET and microMRI for anti-VEGF and anti-PlGF response assessment in an orthotopic murine model of human glioblastoma.

BACKGROUND:Conflicting data exist for anti-cancer effects of anti-placental growth factor (anti-PlGF) in combination with anti-VEGF. Still, this treatment combination has not been evaluated in intracranial glioblastoma (GBM) xenografts. In clinical studies, position emission tomography (PET) using t...

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Main Authors: Mette Kjoelhede Nedergaard, Signe Regner Michaelsen, Thomas Urup, Helle Broholm, Henrik El Ali, Hans Skovgaard Poulsen, Marie-Thérése Stockhausen, Andreas Kjaer, Ulrik Lassen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4332497?pdf=render