Evaluating the frequency and the impact of pharmacogenetic alleles in an ancestrally diverse Biobank population

Evaluating the frequency and the impact of pharmacogenetic alleles in an ancestrally diverse Biobank population

Abstract Background Pharmacogenomics (PGx) aims to utilize a patient’s genetic data to enable safer and more effective prescribing of medications. The Clinical Pharmacogenetics Implementation Consortium (CPIC) provides guidelines with strong evidence for 24 genes that affect 72 medications. Despite...

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Bibliographic Details
Main Authors: Shefali S. Verma, Karl Keat, Binglan Li, Glenda Hoffecker, Marjorie Risman, Regeneron Genetics Center, Katrin Sangkuhl, Michelle Whirl-Carrillo, Scott Dudek, Anurag Verma, Teri E. Klein, Marylyn D. Ritchie, Sony Tuteja
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Translational Medicine
Subjects:
Pharmacogenomics
Electronic Health Records
Genomic analyses
Genetic testing
CPIC guidelines
Online Access:https://doi.org/10.1186/s12967-022-03745-5

Internet

https://doi.org/10.1186/s12967-022-03745-5

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