High fat feeding induces hepatic fatty acid elongation in mice.

BACKGROUND:High-fat diets promote hepatic lipid accumulation. Paradoxically, these diets also induce lipogenic gene expression in rodent liver. Whether high expression of these genes actually results in an increased flux through the de novo lipogenic pathway in vivo has not been demonstrated. METHOD...

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Détails bibliographiques
Auteurs principaux: Maaike H Oosterveer, Theo H van Dijk, Uwe J F Tietge, Theo Boer, Rick Havinga, Frans Stellaard, Albert K Groen, Folkert Kuipers, Dirk-Jan Reijngoud
Format: Article
Langue:English
Publié: Public Library of Science (PLoS) 2009-06-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC2699051?pdf=render