Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes

Summary: Microglia, brain-resident macrophages, require instruction from the CNS microenvironment to maintain their identity and morphology and regulate inflammatory responses, although what mediates this is unclear. Here, we show that neurons and astrocytes cooperate to promote microglial ramificat...

Full description

Bibliographic Details
Main Authors: Paul S. Baxter, Owen Dando, Katie Emelianova, Xin He, Sean McKay, Giles E. Hardingham, Jing Qiu
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721001960