MucoRice-CTB line 19A, a new marker-free transgenic rice-based cholera vaccine produced in an LED-based hydroponic system

MucoRice-CTB line 19A, a new marker-free transgenic rice-based cholera vaccine produced in an LED-based hydroponic system

We previously established the selection-marker-free rice-based oral cholera vaccine (MucoRice-CTB) line 51A for human use by Agrobacterium-mediated co-transformation and conducted a double-blind, randomized, placebo-controlled phase I trial in Japan and the United States. Although MucoRice-CTB 51A w...

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Bibliographic Details
Main Authors: Yoshikazu Yuki, Shiho Kurokawa, Kotomi Sugiura, Koji Kashima, Shinichi Maruyama, Tomoyuki Yamanoue, Ayaka Honma, Mio Mejima, Natsumi Takeyama, Masaharu Kuroda, Hiroko Kozuka-Hata, Masaaki Oyama, Takehiro Masumura, Rika Nakahashi-Ouchida, Kohtaro Fujihashi, Takashi Hiraizumi, Eiji Goto, Hiroshi Kiyono
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Plant Science
Subjects:
MucoRice
rice-based vaccine
cholera
oral vaccine
vaccine development
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2024.1342662/full

Internet

https://www.frontiersin.org/articles/10.3389/fpls.2024.1342662/full

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