Organic dust inhibits surfactant protein expression by reducing thyroid transcription factor-1 levels in human lung epithelial cells

Exposure to organic dust is a risk factor for the development of respiratory diseases. Surfactant proteins (SP) reduce alveolar surface tension and modulate innate immune responses to control lung inflammation. Therefore, changes in SP levels could contribute to the development of organic-dust-induc...

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Bibliographic Details
Main Authors: Kartiga Natarajan, Keerthi Gangam, Velmurugan Meganathan, Koteswara R Gottipati, Courtney Mitchell, Vijay Boggaram
Format: Article
Language:English
Published: SAGE Publishing 2019-02-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425919827360