Unlocking potential inhibitors for Bruton's tyrosine kinase through in-silico drug repurposing strategies

Abstract Bruton's tyrosine kinase (BTK) is a non-receptor protein kinase that plays a crucial role in various biological processes, including immune system function and cancer development. Therefore, inhibition of BTK has been proposed as a therapeutic strategy for various complex diseases. In...

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Bibliographic Details
Main Authors: Mohammed Alrouji, Lizy Sonia Benjamin, Fahad A. Alhumaydhi, Waleed Al Abdulmonem, Saleh Salem Baeesa, Mohd Rehan, Moyad Shahwan, Anas Shamsi, Atiya Akhtar
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-44956-0