Faster Gastrointestinal Transit, Reduced Small Intestinal Smooth Muscle Tone and Dysmotility in the <i>Nlgn3<sup>R451C</sup></i> Mouse Model of Autism

Faster Gastrointestinal Transit, Reduced Small Intestinal Smooth Muscle Tone and Dysmotility in the <i>Nlgn3<sup>R451C</sup></i> Mouse Model of Autism

Individuals with autism often experience gastrointestinal issues but the cause is unknown. Many gene mutations that modify neuronal synapse function are associated with autism and therefore may impact the enteric nervous system that regulates gastrointestinal function. A missense mutation in the <...

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Bibliographic Details
Main Authors: Suzanne Hosie, Tanya Abo-Shaban, Kevin Mou, Gayathri K. Balasuriya, Mitra Mohsenipour, Mohammed U. Alamoudi, Rhiannon T. Filippone, Gabrielle T. Belz, Ashley E. Franks, Joel C. Bornstein, Kulmira Nurgali, Elisa L. Hill-Yardin
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
autism
gut dysfunction
gut motility
gut transit
mouse model
Neuroligin-3
Online Access:https://www.mdpi.com/1422-0067/25/2/832

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https://www.mdpi.com/1422-0067/25/2/832

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