Fast and accurate sCMOS noise correction for fluorescence microscopy

Scientific complementary metal-oxide semiconductor (sCMOS) cameras have advanced the imaging field, but they often suffer from additional noise compared to CCD sensors. Here the authors present a content-adaptive algorithm for the automatic correction of sCMOS-related noise for fluorescence microsco...

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Bibliographic Details
Main Authors: Biagio Mandracchia, Xuanwen Hua, Changliang Guo, Jeonghwan Son, Tara Urner, Shu Jia
Format: Article
Language:English
Published: Nature Portfolio 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13841-8