Activation and detection of HTLV-I Tax-specific CTLs by Epitope expressing Single-Chain Trimers of MHC Class I in a rat model

<p>Abstract</p> <p>Background</p> <p>Human T cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL) in infected individuals after a long incubation period. Immunological studies have suggested that insufficient host T cell response to HTLV-I is a potenti...

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Bibliographic Details
Main Authors: Takayanagi Ryo, Okada Hiroyuki, Nagai Mika, Ohashi Takashi, Shida Hisatoshi
Format: Article
Language:English
Published: BMC 2008-10-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/90