Breaking the Blood–Brain Barrier with Mannitol to Aid Stem Cell Therapeutics in the Chronic Stroke Brain

Blood–brain barrier (BBB) permeabilizers, such as mannitol, can facilitate peripherally delivered stem cells to exert therapeutic benefits on the stroke brain. Although this BBB permeation-aided stem cell therapy has been demonstrated in the acute stage of stroke, such BBB permeation in the chronic...

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Bibliographic Details
Main Authors: Naoki Tajiri, Jea Young Lee, Sandra Acosta, Paul R. Sanberg, Cesar V. Borlongan
Format: Article
Language:English
Published: SAGE Publishing 2016-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368916X690971