Pharmacokinetic Disposition of Amiodarone When Given with an Intralipid Rescue Strategy

Pharmacokinetic Disposition of Amiodarone When Given with an Intralipid Rescue Strategy

While the antiarrhythmic drug amiodarone is commonly used in clinical practice, it has a narrow therapeutic index that can lead to acute overdose. One proposed method to deal with this toxicity is lipid emulsion therapy, which may potentially quench the free amiodarone in blood and prevent its furth...

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Bibliographic Details
Main Authors: Sean N. Avedissian, Michelle Pham, Medha D. Joshi, Marc H. Scheetz, Ashkan Salamatipour, Jeffin M. Panickar, Khrystyna Hlukhenka, Cristina Miglis, Athanasios Chalkias, Theodoros Xanthos
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceutics
Subjects:
amiodarone
pig
HPLC
Intralipid
pharmacokinetic
Online Access:https://www.mdpi.com/1999-4923/13/4/539

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https://www.mdpi.com/1999-4923/13/4/539

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