The risks of using allogeneic cell lines for vaccine production: the example of Bovine Neonatal Pancytopenia
Introduction: Bovine neonatal pancytopenia (BNP) is a hemorrhagic disease that emerged in calves across Europe in 2007. Its occurrence is attributed to immunization of the calf’s mother with a vaccine produced using an allogeneic cell line. Vaccine-induced alloantibodies specific for major-histocomp...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-01-01
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Series: | Expert Review of Vaccines |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/14760584.2017.1249859 |