The risks of using allogeneic cell lines for vaccine production: the example of Bovine Neonatal Pancytopenia

Introduction: Bovine neonatal pancytopenia (BNP) is a hemorrhagic disease that emerged in calves across Europe in 2007. Its occurrence is attributed to immunization of the calf’s mother with a vaccine produced using an allogeneic cell line. Vaccine-induced alloantibodies specific for major-histocomp...

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Bibliographic Details
Main Authors: Lindert Benedictus, Charlotte R. Bell
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Expert Review of Vaccines
Subjects:
Online Access:http://dx.doi.org/10.1080/14760584.2017.1249859