Expression variation of OGG1 and HPRT gene and DNA damage in arsenic exposed industrial workers.

Expression variation of OGG1 and HPRT gene and DNA damage in arsenic exposed industrial workers.

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Arsenic exposure alters redox balance, induces DNA damage, and deregulates many genes. OGG1 gene involved in base repair mechanism, for excision of 8-oxoguanine (8-oxoG) from DNA formed as a result of accumulation of ROS in cell. HPRT gene encode transferase enzymes involved in purine recycling mech...

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Bibliographic Details
Main Authors: Zertashia Akram, Ishrat Mahjabeen, Muhammad Umair, Muhammad Fahim, Mahmood Akhter Kayani, Lulu Fatima, Malik Waqar Ahmad, Sarwat Jahan, Tayyaba Afsar, Ali Almajwal, Nawaf W Alruwaili, Iftikhar Ali Khawar, Suhail Razak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0273211

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https://doi.org/10.1371/journal.pone.0273211

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